W. M. Keck Institute for Attofluidic
Nanotube-Based Probes
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W. M. KECK INSTITUTE TEAM
FACULTY
Dr Yury Gogotsi
Professor Yury Gogotsi is Trustee Chair Professor of Materials Science and Engineering, Drexel University and Director of the A. J. Drexel Nanotechnology Institute. He obtained his Ph.D. in Metallurgy, Physical Chemistry from National Technical University of Ukraine 'Kyiv Polytechnic Institute', 1986 and D.Sc. from Materials Engineering, National Academy of Sciences, Ukraine, 1995. Prior to joining Drexel University he was faculty of Mechanical Engineering at University of Illinois at Chicago, 1996-2000. Prof. Gogotsi is a recipient of numerous national and international research awards, including Fellow of the American Association for the Advancement of Science (AAAS), and Fellow of the Electrochemical Society. Prof. Gogotsi has experience of over 25 years in the fields of materials science and nanonotechnology, he holds over 30 patents, he authored 2 books, edited 12 books, contributed to 14 book chapters, published more than 300 papers in peer-reviewed journals including 3 papers in Nature and 2 papers in Science. He is an editor of Carbon (Elsevier), which is the highest ranked journal in the carbon materials field.
DR GARY FRIEDMAN
Gary Friedman received his Ph.D. at the University of Maryland College Park in 1990. From 1990 until 2001 he has been a faculty in the Department of Electrical and Computer Engineering at the University of Illinois at Chicago. Since 2001 he has been with the Departments of Electrical and Computer Engineering at Drexel University in Philadelphia. In 2004 he joined the Department of Surgery at the Drexel College of Medicine. Gary Friedman's interests are in applications of electrical and magnetic phenomena to medicine and biology. His recent work involved development of miniature coils for Nuclear Magnetic Resonance imaging of cells, magnetic manipulation and separation in lab-on-a-chip applications, cellular probing using carbon nanotubes, magnetically targeted drug delivery in cardiovascular and orthopedic applications. He has also initiated work on applications of non-thermal plasma in medicine. Dr. Friedman's research in nanotechnology includes study of self-assembly of magnetic nano-particles and applications of magnetic nano-patterns and nano-particles to fabrication of biochemical sensors and sensor arrays. He is also developing miniature Nuclear Magnetic Resonance (NMR) sensors and systems. Dr. Friedman's work in the area of Micro-Electro-Mechanical Systems (MEMS) includes micro-fluidic systems for delivery of liquid micro-drops and the use of liquid micro-drops for adaptive optical devices and switches. He is also actively involved in theoretical and numerical modeling of hysteresis related phenomena in complex systems such as magnetic particle assemblies and nano-structured magnetic materials.
DR JANE AZIZKHAN-CLIFFORD
Professor Jane Azizkhan-Clifford is Chair of the Department: Biochemistry and Molecular Biology, Drexel University. She obtained her Ph.D. in Developmental and Cellular Biology, University of Maryland, 1978. Her research interests are Cellular response to DNA damage, regulation of gene expression, cellular proliferation and the cell cycle.
DR BRADLEY E. LAYTON
Dr. Bradley E. Layton is an assistant professor at the Department of Mechanical Engineering and Mechanics. His research interests are Cell and Protein Mechanics, Protein Evolution with particular regard for the evolution of tubulin and collagen, Soft-tissue mechanics, Nanoscale Biomechanics; Mechanics of Diabetic Neuropathy, Hematology on a chip, Highly Parallel Nanoscale Force Measurement, Nanomanipulation, Atomic Force Microscopy, MechanoEvolution, and Sustainable transportation.
DR ELISABETH S. PAPAZOGLOU
Professor Elisabeth S. Papazoglou is faculty at the School of Biomedical Engineering, Science & Health Systems, Drexel University. She obtained her Ph.D. from Case Western Reserve University, Macromolecular Science & Polymer Engineering, 1988. Her research interests include Skin Research, Wound Healing, Deployment of Non-Invasive Technologies for Skin Characterization, Correlation of Spectroscopic/Imaging Information to Skin Chemistry, Wound Healing, Transdermal Delivery, and Nanosomes.
DR MICHAEL BOUCHARD
Professor Michael Bouchard is an assistant professor at the Department of Biochemistry and Molecular Biology at Drexel University. He obtained his Ph.D. in Microbiology from Columbia University in 1997. His research interests include Liver Cancer, hepatocyte transformation, calcium signaling, apoptosis, cell proliferation, alcohol, novel liver models.
POSTDOCS AND STUDENTS
DR. ZULFIYA ORYNBAYEVA
Zulfiya Orynbayeva is a Research Associate at the Materials Science and Engineering Department at Drexel University and a Visiting Assistant Professor at the School of Biomedical Engineering, Science and Health System, Drexel University. Dr. Orynbayeva received M.Sc. in Biophysics from Tashkent State University (USSR) in 1989 and earned Ph.D. in Biophysics from the same University in 1994. She worked as Lecturer at Almaty State University and Senior Researcher at Institute of Problems in Biology and Biotechnology at Al-Farabi Kazakh National University in Kazakhstan. After completing the postdoctoral training at Ben-Gurion University of the Negev, she received a staff scientist position at Ilse Katz Center for Meso- and Nano-Scale Science and Technology in Israel.
Dr. Orynbayeva’s research interests include nanomedicine, single cell and single organelle probing, cell proteomics, physiology and mechanics. Her special interests relate to various problems with key-involvement of mitochondria, characterization of mitochondria metabolic activity, study of mechanisms mitochondria PTP functioning and ROS generation in context of neurodegenerative diseases and cancer. Dr. Orynbayeva specializes on applications of different spectroscopic and microscopic techniques to intact and permeabilized cells and tissue samples for investigation of molecular intra- and intercellular signaling.
Dr. Orynbayeva's Selected Publications
DR. SAYAN BHATTACHARYYA
Dr. Sayan Bhattacharyya is involved in fabrication of the carbon nanoprobes, functionalization of the probes, measurement and analysis of electrical conductivity of the nanopipettes, and synthesis of nanoparticles using corona discharge in liquids. He received his Ph.D degree from the Department of Chemistry, Indian Institute of Technology Kanpur (INDIA) in 2006 and M.Sc (Physical Chemistry) from Department of Chemistry, Kalyani University, West Bengal (INDIA) in 1998. In June 2006, he joined the Department of Chemistry and Bar-Ilan University Center for Advanced Materials and Nanotechnology (ISRAEL), as a postdoctoral researcher with Professor Aharon Gedanken. In April 2008, he joined Professor Yury Gogotsi's group at Drexel Nanotechnology Institute as postdoctoral researcher. His research interests include nanomaterial synthesis with non-thermal corona discharge, carbon nanomaterials, nanoprobes for intracellular drug delivery, mesoporous materials, spintronics and magnetic nanostructures. He has published his research work in a decent number of peer reviewed journals and is currently the group leader of carbon nanotube research in Professor Gogotsi's group.
MS. ELINA A. VITOL
Ms. Elina A. Vitol is presently pursuing her Ph.D. degree from the Department of Electrical and Computer Engineering Department under the supervision of Prof. Gary Friedman, and Prof. Yury Gogotsi. Her research interests include Nanoprobes for intracellular surface-enhanced Raman spectroscopy, Surface Plasmon Resonance effects on Raman scattering enhancement, and Nanofluidic cellular probes based on Carbon Nanotubes. She has hands-on experience in experimental techniques such as Micro-Raman spectroscopy, Surface-Enhanced Raman spectroscopy, Scanning Electron Microscopy, Laser scanning confocal fluorescence microscopy, Synthesis of gold nanoparticles, Physical vapor deposition of thin films, Aseptic cell culture, Optical Profilometry, Alumina template based technique for CVD growth of carbon nanotubes, and Western blot. Ms. Vitol received her MS degree in 2006 under the supervision of Prof. Timothy P. Kurzweg, Drexel University, Electrical and Computer Engineering Department and worked on application of white light scattering spectroscopy for morphological characterization of epithelial tissues. Before joining Drexel University, she worked on characterization and testing of an optical encoder for linear displacements, as undergraduate research assistant at St. Petersburg State University of Fine Mechanics and Optics.
MR. RIJU MOHAN SINGHAL
Mr. Riju Mohan Singhal is currently a 2nd year PhD student in Materials Science and Engineering, at Drexel University under the supervision of Prof Yury Gogotsi. He obtained his B-Tech. degree in Chemical Engineering from the Indian Institute of Technology Kanpur (2007). His research interests include Chemical Vapor Deposition of Carbon, Application of Carbon nanotubes in nano-fluidics, Multifunctional carbon probes for intra-cellular studies and Convective Heat Transfer. His achievements include best poster awards in 2009 on his research of nanoscale intracellular probes, IIChE award for the best paper by an undergraduate student in Chemical Engineering in a high impact factor journal for the year 2007-08, sponsored by Chemical Weekly, best poster presentation and best overall presentation at SCHEMCON 2005 and IIChE award (sponsored by VICAL) for the best undergraduate student presentation for the year 2005.
DR. JUN JIE NIU
Dr. Jun Jie Niu is presently working as postdoctoral research fellow at the A.J. Drexel Nanotechnology Institute (DNI), Drexel University with Prof. Yury Gogotsi from April, 2009 onwards. He obtained his M.Sc. and Ph.D. candidate from Zhejiang University, China in 2005. Previously he worked as Teacher at School of Materials Science and Engineering, Shanghai Jiao Tong University, China. His research interests include Functional carbon nanomaterials with intracellular SERS spectroscopy with nanopipette,
Self-organized nanomaterials (nano-particles, nano-wires, and nano-tubes), Catalyst support with carbon nanomaterials in fuel cells (carbon nanocages and carbon nanotubes), and Hydrophobic surface with chemically modified nanowire coating. Dr. Niu has published more than 60 papers in peer-reviewed journals including "Adv.Mater.", "JPCB ", "JMC" were published. 13 China invention patents have been applied.
DR. MICHAEL SCHRLAU
Michael Schrlau earned his BS in Mechanical Engineering and Materials Science from the University of Pittsburgh in 1998. From 1998 to 2004, Michael worked for Kimberly-Clark Corp in roles ranging from R&D engineering to operations management. In 2009, Michael earned his PhD in Mechanical Engineering and Applied Mechanics at the University of Pennsylvania for his research in carbon-based biological nanoprobes. After completing a postdoctoral fellowship in the Department of Pharmacology at Temple University, he joined the Department of Materials Science and Engineering at Drexel University as a Research Assistant Professor in November 2009. Michael’s research focuses on developing novel micro-/nanoscale devices for biomedical applications and micro-/nanofluidic study. His research was featured on the cover of Nanotechnology and was listed as one of the most accessed in 2008. Michael’s research appears in numerous peer-reviewed journal articles, book chapters, and intellectual property that has resulted in technology licensure and technology transfer to small business. Michael is also active in nanotechnology and nanoscience outreach programs in Philadelphia area school districts.
MR. JUSTIN RONNIE WARREN
Mr. Justin Ronnie Warren is pursuing BS/Ph.D. degree at the Department of Mechanical Engineering at Drexel University under the supervision of Prof. Bradley Layton. He is presently involved in testing the mechanical properties of the carbon nanoprobes using nanoindentation technique. He is experienced in equipments such as Scanning Electron Microscope, Nanoindenter, Pt/Pd Sputter Coater, Micropipette Puller, Olympus Microscope with Eppendorf Mircomanipulators. He is well versed in software such as AutoCAD, Pro/Engineer, Matlab, Maple, LaTex, MS Office Suite. The awards and honors of Mr. Warren are A.J. Drexel Merit Scholarship, 2008-Present, Academic Dean's List, 2008, Drexel University Pennoni Honors College, 2008-Present, and first Place in Arkansas State Junior Academy in Engineering, 2008.
MR. BRENT BOYD
Mr. Brent Boyd has been a broad spectrum manufacturing professional for 17 years, as well as a lifetime scientist. Currently, he is a graduate researcher at Drexel University in the Mechanical Engineering and Mechanics department. He has a number of research interests in the fields of materials science, chemistry, robotics, machine tool science, internal combustion engines, botany, mycology, marine biology, ecological science, alternative energy, and gourmet cooking. His previous education encompasses Mastercam X, Robert Morris University, 2006, Post-Bach studies in Drafting, Mathematics, and Solid Works, Modesto J.C. 1999. His research skills are operation of a Digital Instruments Nanoscope 3000 Atomic Force Microscope, Advanced programming and setup of vertical and horizontal CNC machine centers, CNC and conventional Machinist/Toolmaker skills, CAD drafting and engineering in several software packages
Comprehensive Blueprint Reading and GD&T, MIG and TIG welding, Comprehensive automotive mechanic skills/performance engine development, Field botany, mycology, and marine biology research skills, Precision inspection/analysis and reverse engineering, Research and development/Prototype manufacturing.
PAST MEMBERS
DR. DAVID A. STAACK
Dr. David A. Staack received his Ph.D. degree from the Department of Mechanical Engineering at Drexel University in 2008. He is currently appointed as Assistant Professor at the Texas A&M University, Mechanical Engineering. Dr. Staack obtained his ME degree from Princeton University in 2004 and BS/MS from University of Virginia, BS/MS in 2000. His research interests include Non-thermal Plasmas, Micro- and Nano-Scale plasmas, Electric Propulsion for Spacecraft, Plasma Enhanced Materials Processing and Synthesis, Plasma Enhanced Fuel Conversion and Combustion Biomedical Plasma Applications, Laser and Spectroscopic Diagnostics. Dr. Staack has shown the multi-elemental analysis in liquids on the ppm level, using non-thernal nanoscale corona discharge, which is a useful tool for detecting very small amount of ions in biological cells.
DR. NADARAJAN SUNDAR BABU
Dr. Nadarajan Sundar Babu is presently employed as Research Assistant Professor at the School of Biomedical Engineering, Science and Health Systems, Drexel University. His research interests include Nano-optical biosensors, Electrochemical biosensors, Surface enhanced Raman spectroscopy, Drug delivery vehicle design and transdermal drug delivery, Micro and nanofluidics. Dr. Babu receive his Master of Science degree in Applied Chemistry, 1994 from Madurai Kamaraj University, Madurai, Tamil Nadu, India and Ph.D. in Materials Science in 2000 from University Malaya, Kuala Lumpur, Malaysia. Before joining Drexel University as Research Postdoctoral Associate in 1999, he worked as Visiting Scholar at the University of West Florida, Pensacola, Florida.
DR. KATHLEEN B. ALLEN
Dr. Kathleen B. Allen is an Associate in Exponent's Biomechanics practice. Her area of expertise includes the response of biological systems to mechanical stimuli, from the macroscale (organism) level down to the microscale (cellular) level. At Exponent, Dr. Allen's work has focused on human kinematics and injury mechanisms in motor vehicle, fork-lift, and slip-and-fall accidents. Additionally, Dr. Allen has investigated the mechanical failure of the heart during mitral valve replacement surgeries involving both mechanical and biological prostheses. Dr. Allen's studies have been focused in solid mechanics, dynamics, human physiology, and computer simulation.
Prior to joining Exponent, Dr. Allen was a research assistant in the Department of Mechanical Engineering and Mechanics, Drexel University working in the Cell and Protein Mechanics Laboratory, at Drexel University. Additionally, she has worked as a research assistant at Baylor College of Medicine in Houston, Texas, and at the National Nanotechnology Laboratories in Lecce, Italy. Dr. Allen's interdisciplinary research has focused on problems that lie along the interface of engineering and medical technologies. Her work has included a wide range of elements, including micromanipulation, nanomanipulation, high resolution imaging, and computer simulation. By applying the fundamental theories of mechanics to biological membranes and vesicles, Dr. Allen worked to minimize the damage that cells experience during single-cell manipulation and injection.